应我校生物与食品工程学院、科研处邀请，瑞典乌普萨拉大学Hesham R. El-Seedi教授将在我校做学术讲座，欢迎广大老师届时前往。
讲座时间：2024年5月21日（周二）下午3:00-4:00
讲座地点：生物与食品工程学院会议室（实训楼A1107）
主讲人简介：
Hesham R. El-Seedi 教授致力于从药用植物、海洋、蜂产品、合成和生物合成中分离和阐明生物活性天然产物的结构。他是日本庆应义塾大学 JSPS 研究员。在其职业生涯中，曾在国际公认的先驱实验室工作，包括瑞士日内瓦大学、梅努菲亚大学、瑞典皇家理工学院、斯德哥尔摩大学和乌普萨拉大学。已在同行评审的国际期刊上发表了 420 多篇同行评审的国际研究文章和科学论文、评论、章节，其中包括《柳叶刀》（当前 IF 约 168.7）。曾在全球200多场国际科学会议上介绍自己的研究成果并获奖。他是一些国际期刊的编辑和主编。
Hesham R. El-Seedi working in isolation and structure elucidation of biologically active natural products from medicinal plants, marine, bee products, synthesis and biosynthesis. Hesham is a fellow of JSPS, Keio University, Japan. Throughout his carrier, he worked in pioneer internationally recognized laboratories including Geneva University, Switzerland; Menoufia University, KTH; Stockholm University, Uppsala University, Sweden.
He has published more than 420 peer-reviewed international research articles and scientific papers, reviews, chapters in Peer-Reviewed International Journals among them: The Lancet (Current IF around 168.7).
He has presented his research at over 200 International scientific conferences worldwide and received awards. He is Editor and as Editor of some International Journals.
讲座摘要：
几千年前，验证食物和草药的功效研究已经在全球范围内进行，特别是在中国和中东。其中一些研究成果促成了以天然产品为基础的药物生产。在本次讲座中，将介绍一些具有有益健康功效的潜在天然产品。首先介绍传统植物的重要性，例如Allium sativum和A. cepa(洋葱)(古兰经植物)，它们可用于治疗2型糖尿病、冠心病、肥胖、高胆固醇血症和高血压。此外，仙人掌科植物的重要性自古以来就得到了证明。例如，我们从仙人掌Lophophora williamsii中发现的美斯卡灵，研究表明该化合物具有精神药物特性，仙人掌类样品似乎是有史以来最古老的植物药物，即早在5700年前。另一种传统上用于降低血压、调节体温、促进排尿和导致抗氧化剂消耗的植物是Karkadeh。代谢工具证明其抗高血压的烹饪特性和治疗效果是由于花青素的存在，同样，无花果(梧桐无花果)提取物的大规模代谢物谱分析被发现在实验感染的兔子中抑制肠道球虫病(体内研究)。本次讲座将讨论绿茶，作为一种非发酵茶(Camellia sinensis)，其生物活性成分和抗氧化能力是通过近红外光谱结合群智能算法确定的。最后，讨论将处理利用先进的微胶囊技术来提高基于酚类化合物的生物利用度的2型糖尿病治疗。因此，微胶囊化的多酚，而不是游离化合物，可以有效地缓解这个问题。
Since thousands of years ago, studies have been carried out globally especially in China and the Middle East to verify the efficacy of foods and medicinal herbs. Some of the research findings have led to the production of natural products sources-based medicines. In this talk, some potential natural products with beneficial health effects will be presented. First, the importance of traditional plants i.e., Allium sativum and A. cepa (onion) (Quranic Plants); that are used against diabetes type 2, coronary heart disease, obesity, hypercholesterolemia, and hypertension. Moreover, the importance of Cactaceae plants was proved since ancient times; for example, our mescaline discovery from peyote cactus Lophophora williamsii. shown that the compound displayed psychotropic properties and peyote samples appear to be the oldest plant drug ever i.e. as long as 5700 years ago. Another plant that is traditionally used to reduce blood pressure, regulate body temperature, enhance urination, and cause depletion of antioxidants is Karkadeh (Hibiscus sabdariffa (roselle)). Its anti-hypertensive culinary properties as well as therapeutic effects were proved by metabolic tools to be due to the presence of anthocyanins, and similarly, the large-scale metabolite profiling of Ficus sycomorus (Sycamore Fig) extract, were found to inhibit intestinal coccidiosis in experimentally infected rabbits (in vivo studies). The talk will tackle the Green tea, as a non-fermented tea (Camellia sinensis), and its bioactive constituents and antioxidant capability were determined by NIR spectroscopy coupled with swarm intelligence algorithm. Finally, the discussion will handle the utilization of advanced microencapsulation technology to enhance Diabetes Type 2 treatment based on bioavailability of phenolic compounds. Thus, microencapsulated polyphenols, instead of free compounds, can effectively alleviate the problem.
组织单位：生物与食品工程学院 科研处
